Endocrine Abstracts

Background and aims: Pituitary apoplexy (PA) is a rare clinical syndrome due to pituitary hemorrhage or infarction. It is an emergent and potential life-threatening complication of pituitary adenomas if not managed properly. It is usually characterized by the sudden onset of one or more of the following: severe headache, visual disturbance, nausea/vomiting, and or altered mental status. We aimed to present clinical and biochemical characteristics as well as management of patie...

Introduction: Hypothyroidism in pregnancy is a topic widely studied in recent years, especially in those women with positive autoimmunity. However, usually the only determination of antibodies that is made is the thyroid antiperoxidase antibodies (anti-TPO). In this study we wanted to know what incidence of anti-thyroglobulin antibodies (anti-Tg) our pregnant women present and what repercussion they can have on thyroid function.Materials and methods: Ant...

Object: Nonfunctioning pituitary adenomas can experiment recurrence and/or progression (R/P) several years after surgery in about 15–50% of patients. There is few evidence about risk factors that could predict R/P. The aim of this study is to identify them and describe our experience through a long term of follow-up in pituitary macroadenomas.Methods: Retrospective cohort analysis of 64 patients who underwent surgery between 1990 and 2013. The main ...

Introduction: The global patterns of aberrant DNA methylation in thyroid cancer are not known. In this study, we have used DNA methylation arrays to determine, for the first time, the genome-wide promoter methylation status of different subtypes of thyroid tumors.Material and methods: We analyzed a cohort of 54 snap frozen thyroid samples (thirteen papillary tumors, six follicular, eleven anaplastic, twenty medullar and four normal tissue samples). Also ...

Purpose: At the beginning of 2016, radiofrequency ablation of benign thyroid nodules began to be carried out at the Central University Hospital of Asturias (Spain). The aim of this study was to evaluate the results obtained by the moment with the aforementioned technique.Methods: It is a descriptive study carried out through the data obtained during the process and the subsequent analytical and ultrasonographic follow-up. In addition, patient surveys hav...

Introduction: There is scarcity of data on the recurrence and/or progression (R/P) rate in nonfunctioning pituitary adenomas (NFPAs) after surgery and the risk factors that can predict this outcome. So the aim of this study was to analyze a large series of NFPAs with a long follow-up after surgery, focusing on the evaluation of R/P rate and the risk factors associated with it.Methods: Retrospective cohort analysis of 164 patients with NFPAs from 3 differ...